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Dupuytren Research Group Blog

How the FDA sees Collagenase for Dupuytren’s

Why is it taking so long for collagenase injection treatment to be available to treat Dupuytren’s? Trials have been ongoing for over 10 years. The answer: collagenase is an extremely

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Abstracts can be misleading

Unlike proximal interphalangeal joint contractures from Dupuytren’s, metacarpophalangeal joint contractures usually respond so well to fasciectomy or fasciotomy that joint capsule or ligament release is generally not a consideration. Because

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Myofibroblast Biology

Myofibroblast biology is at the heart not only of Dupuytren’s, but of other diseases not related to Dupuytren’s. Myofibroblasts are major players in pulmonary fibrosis, cirrhosis, renal fibrosis and arteriosclerosis.

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