Dupuytren’s and Associated Conditions
Dupuytren’s is associated with three conditions, Ledderhose, Peyronie’s and frozen shoulder. These all share a similar biology at a cellular level. Dupuytren’s is also associated with other conditions, such as diabetes, alcoholism, epilepsy, advanced HIV for reasons which are less clear. Is Dupuytren’s a risk factor for some of these other health issues or is […]
Genes, enzymes and Dupuytren’s: the alphabet name game.
A proteinase is an enzyme which breaks down proteins. Metalloproteinases (MPs) are proteinases with a molecular structure and function involves a metal atom, usually zinc. Matrix Metalloproteinases (MMPs) are MPs which act outside of cells, in the tissue matrix. Human collagenases are MMPs which break down different types of collagen. Membrane-type MMPs (MT-MMPs) are MMPs […]
