Transforming Factor ß | Dupuytren Research Group

Transforming Factor ß

RNA, Growth Factors and Dupuytren’s

Sorting out the genetic basis of Dupuytren’s is not simply a matter of finding out which genes are involved. The goal is to understand the biochemistry of exactly what these specific genes do to either start or fail to stop the process of Dupuytren’s. Cell biology is always a domino like set of events with […]

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ß Catenin, Transforming Factor ß and Dupuytren’s

The physical changes associated with Dupuytren’s are similar to the process which heals open wounds through contraction and collagen production. Thanks to sophisticated laboratory research, the molecular controls for this process are beginning to be understood. See http://multimedia.mcb.harvard.edu/anim_innerlife.html for an amazing animation of how molecular cellular controls act like tiny physical machines. In Dupuytren’s, two […]

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