General

Biomarkers in Dupuytren Disease
IDDB, biomarkers and big data to cure Dupuytren disease

The International Dupuytren Data Bank (IDDB) will focus on Dupuytren biomarkers Why are biomarkers important for Dupuytren disease? Dupuytren contracture is an effect, not a cause. Think of fever. Fever is an effect of infection, drug reaction, or something else. Just treating the effect – the fever – doesn’t cure the cause. ‌‌ You have to find […]

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GivingTuesday Deal for the Dupuytren Foundation
On: Dec 1, 2015
By: Charles Eaton

It has been a great year – thanks to you! We’ve launched the International Dupuytren Data Bank (IDDB) – research for a cure, to be the largest Dupuytren study in history. Now that the IDDB is underway, your support is more important than ever. Please consider increasing your year-end gift to the Dupuytren Foundation this year […]

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Three types of Dupuytren disease?

It’s important to understand the difference between Dupuytren disease (any Dupuytren like changes in the hand – with or without contracture) and Dupuytren contracture (a bent finger due to Dupuytren like changes). An unsolved issue is variability of disease. It is not known what percent of people with early Dupuytren changes (a lump, a cord without contracture) will […]

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Options For Severe Dupuytren Recontracture 2/2

The three traditional treatments for severe recurrent Dupuytren contracture are PIP joint fusion, dermofasciectomy and amputation. These have been reviewed here. The list of alternative approaches is growing, particularly for the most difficult problem of PIP joint recontracture. The problem is that over time, the tendons and ligaments of a bent PIP joint change and […]

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Will Winford’s Dupuytren Challenge: Climbing El Capitán for a Cure

Dupuytren disease is a challenge. So is climbing straight up the side of a tall mountain with your bare hands. Today Will Winford, a 27 year old rock climber with Dupuytren disease, begins his conquest of both – climbing  the 3000 vertical feet of El Capitán and using this to help raise awareness of Dupuytren disease. Find […]

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The Knowledge Gap
On: Jul 29, 2015
By: Charles Eaton

Dupuytren disease has fallen through a gap in a system which ordinarily leads to better and better disease treatment. One side of the gap is that at its core, Dupuytren disease is a medical disorder, from some subtle biologic imbalance. The other side is that although Dupuytren disease does many things, Dupuytren hand deformity has […]

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Blue Eyes, Dupuytren Disease, and Alcoholism
On: Jul 19, 2015
By: Charles Eaton

  A recent study linked blue eyes with genetic risk for alcoholism. Interesting, because Dupuytren disease is more common in people with light colored eyes and according to some studies, Dupuytren is linked to chronic alcoholism. It’s a match! Or is it? Other studies conclude alcoholism is not a risk for Dupuytren disease. Both Dupuytren and blue eyes are more common in […]

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Big data editorial
On: Nov 9, 2014
By: Charles Eaton

The path to understanding Dupuytren disease is being built on evolving technologies: patient crowdsourcing; genetic analysis; big data. We’re not alone. This editorial discusses the impact of big data on medical research:http://www.amjorthopedics.com/uploads/media/ajo043090399.pdf.

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International Dupuytren Society Survey Now Available
On: Jul 29, 2014
By: Charles Eaton

Do you or does someone you know have either Dupuytren Disease, Ledderhose Disease, or both? Here’s a message from the International Dupuytren Society: “The International Dupuytren Society, the Ledderhose Blog, and the British Dupuytren Society have jointly developed a questionnaire targeting patients suffering from Dupuytren and/or Ledderhose disease. Please share your experience with these diseases, […]

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On: Aug 18, 2013
By: Charles Eaton

Dupuytren Foundation August 2013 The Dupuytren Foundation may have seemed quiet, but there’s been quite a bit of internal activity reorganizing and streamlining for the last several months. This newsletter marks a milestone of consolidating all of our electronic resources into one system, which will make it easier for you to stay in touch and […]

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