Xiaflex | Dupuytren Research Group

Xiaflex

2015 Dupuytren Symposium
2015 International Symposium on Dupuytren Disease

The May 2015 International Dupuytren Symposium in Groningen, The Netherlands was very productive. A textbook based on the proceedings is in the works. Video presentations are rolling out on http://Dupuytren.tv

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Personal experiences with Xiaflex and Needle Aponeurotomy

Xiaflex is now available, and is generating reports by both traditional writers and self published social media authors. There are now two minimally invasive treatments for contractures due to Dupuytren’s disease – Xiaflex injection and needle aponeurotomy – with relative advantages and disadvantages of each. The following video was made by a Dupuytren’s patient, documenting […]

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Xiaflex Pricing

Auxilium has moved closer to product availability of Xiaflex collagenase injection for the treatment of Dupuytren’s contracture by announcing the wholesale drug price: $3250.00 for a single treatment dose. For those who think that this seems high, consider this in perspective. There are many categories of pharmaceutical products. Most commonly available pharmaceuticals are classified as […]

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Needle Aponeurotomy and Xiaflex compared

Xiaflex (Collagenase) has finally been approved by the FDA for the treatment of Dupuytren’s contracture. When work began on the development of collagenase to treat Dupuytren’s contracture, the bar was pretty low: anything better than fasciectomy in terms of either safety or efficacy would be a great advance. No other treatment options were available in […]

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FDA approves Collagenase for Dupuytren’s

Collagenase (Xiaflex) has been approved by the FDA for treatment of Dupuytren’s contracture, after years of intensive laboratory and clinical trials. Collagenase enzymatic  fasciotomy is more similar to needle fasciotomy than to either open fasciotomy or fasciectomy in terms of rapid recovery and low complication rate. Compared to needle release, collagenase enzymatic fasciotomy should eventually […]

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A Sampling of Patient Information Brochures on Dupuytren’s
On: Jan 30, 2010
By: Charles Eaton

What do health care providers think you should know or want to know about Dupuytren’s? Here is a sampling of patient information materials from the government https://dupuytrens.org/DupPDFs/2010_NHS-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2010_OBS-ptinfo.pdf, organizations of hand surgeons https://dupuytrens.org/DupPDFs/2010_AAHS-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2010_ASSH-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2010_BSSH-ptinfo.pdf, individual physicians and hospitals https://dupuytrens.org/DupPDFs/2010_eHand-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2010_KWO-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2002_Hurst-ptinfo.pdf, https://dupuytrens.org/DupPDFs/2010_Lancashire-ptinfo.pdf and hand therapists https://dupuytrens.org/DupPDFs/2010_Kramer-ptinfo.pdf. Of course, a wide range of information is […]

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Needle Aponeurotomy for Dupuytren’s

Needle aponeurotomy for Dupuytren’s contracture is a type of fasciotomy performed under local anesthesia. Compared to fasciectomy, it is less of an ordeal for the patient in terms of both procedure and recovery and has a lower complication rate. This report (full text: http://www.dupuytrenfoundation.org/DupPDFs/2008_Cheng_1610.pdf) reviews one group’s experience with needle aponeurotomy.

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