Collagenase (Xiaflex) has been approved by the FDA for treatment of Dupuytren’s contracture, after years of intensive laboratory and clinical trials. Collagenase enzymatic  fasciotomy is more similar to needle fasciotomy

The hunt is on for the genetic basis of Dupuytren’s. A interesting analysis of the chromosome patterns found in Dupuytren’s tissue found a variety of genetic abnormalities and the unexpected

Needle aponeurotomy for Dupuytren’s is not that new. It’s a new twist on the very first operation described for Dupuytren’s, percutaneous fasciotomy, which was performed by Cooper years before Dupuytren’s