Dupuytren’s is one manifestation of a systemic fibrotic disorder that can also show up as Ledderhose, frozen shoulder or Peyronie’s disease. Fortunately, the majority of people affected show only one

Two methods of investigating Dupuytren’s have been used: Demographic – family studies, associations with medications, activities, other diseases; and Biological – tissue analysis. The big biologic breakthrough came in 1972

The palmar fascia in Duputren’s contracture does not contract like a muscle: it’s more like the effect of an army of tiny rachets. Adjacent parallel strands of collagen are grabbed