Time to pause and look at the big picture. Here is a balanced overview of the history, biology, etiology and epidemiology of Dupuytren Disease: https://dupuytrens.org/DupPDFs/2003_Thurston.pdf

Myofibroblasts are part of the normal tissue repair response to almost all injuries: cut, crush, burn, chemical injury, infectious gangrene, and others – with one exception: freeze injury. Freeze burns

A specific gene has not been definitively associated with Dupuytren’s, but the best evidence suggests that the primary cause is genetic. There are factors which alter risk, such as diabetes