Dupuytren Research Group Blog

A landmark advance in understanding Dupuytren’s

Two methods of investigating Dupuytren’s have been used: Demographic – family studies, associations with medications, activities, other diseases; and Biological – tissue analysis. The big biologic breakthrough came in 1972

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Smooth Muscle Actin in Dupuytren’s Contracture

The palmar fascia in Duputren’s contracture does not contract like a muscle: it’s more like the effect of an army of tiny rachets. Adjacent parallel strands of collagen are grabbed

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CMMS therapy for stiffness after fasciectomy for Dupuytren’s

Stiffness is a common problem after fasciectomy, particularly loss of flexion, and can be resistant to stretching exercises or splints. This therapy program, incorporating a combination of casting and active

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