DUPUYTREN LITERATURE: TNF INHIBITORS

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Medline Title Search (Dupuytren + TNF)

Selected Publications

• Izadi D, Layton TB, Williams L, McCann F, Cabrita M, Espirito Santo AI, et al. Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis. Sci Adv. 2019;5(12):eaay0370. (PDF)
• Nanchahal J, Ball C, Swettenham J et al. (2017) Study protocol: A multi-centre, double blind, randomised, placebo-controlled, parallel group, phase II trial (RIDD) to determine the efficacy of intra-nodular injection of anti-TNF to controldisease progression in early Dupuytren’s disease, with an embedded dose response study. [version 2; referees: 2 approved] Wellcome Open Research 2017, :37 (PDF)
• Nanchahal J, Ball C, Swettenham J, et al. (2018) Anti-Tumour Necrosis Factor Therapy for Dupuytren’s Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial. EBioMedicine journal 2. The Authors: 37. DOI: https://doi.org/10.1016/j.ebiom.2018.06.022. (PDF)
• Png ME, Dritsaki M, Gray A, Pinedo-Villanueva R, Rivero-Arias O, Nanchahal J. Economic evaluation plan of a randomised controlled trial of intra-nodular injection of anti-TNF and placebo among patients with early Dupuytren’s disease: Repurposing Anti-TNF for Treating Dupuytren’s Disease (RIDD). Wellcome Open Res. 2018;3:156. (PDF)
• Verjee LS, Verhoekx JSN, Chan JKK, et al. (2013) Unraveling the signaling pathways promoting fibrosis in Dupuytren’s disease reveals TNF as a therapeutic target. PNAS 110(10). 2013/02/23.: E928-37. (PDF)