Dupuytren biology is provoked by mechanical stress. If you have Dupuytren disease, don’t stop exercising, but look into ways to reduce the stress on your palms when you work out. You can cushion or shield your palms with workout gloves, pull up hooks, or pull up pads. Also, anything which increases the diameter of your grip reduces the amount of shearing stress on your palm when you grip. Take advantage of this by using padded gloves (welder’s gloves are good), larger grips on weights, golf clubs and tennis racquets.