Red wine and yellow curry to prevent Dupuytren’s? | Dupuytren Research Group

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Red wine and yellow curry to prevent Dupuytren’s?

Could a yellow curry dinner and a glass of red wine be good for Dupuytren’s? Possibly. Dupuytren’s is a fibrotic condition, something it shares with other disorders. There is a great deal of ongoing research into the biology of fibrosis and its possible treatment. Two studies suggest that diet may have an helpful influence on excessive fibrosis, at least in special circumstances. In “Protective Effects Of Curcumin Against Amiodarone-Induced Pulmonary Fibrosis In Rats” (full text: http://www.dupuytrenfoundation.org/DupPDFs/2003_Punithavathi.pdf), researchers found a protective effect against lung fibrosis of curcumin, found in turmeric, the spice which gives the yellow color to curry and yellow rice. Another group reported in “Ochratoxin A–Induced Renal Cortex Fibrosis and Epithelial-to-Mesenchymal Transition: Molecular Mechanisms of Ochratoxin A-Injury and Potential Effects of Red Wine” (full text: http://www.dupuytrenfoundation.org/DupPDFs/2005_Gagliano.pdf) a protective effect of red wine against kidney fibrosis. These studies were performed on rats, testing against drugs known to cause fibrosis, which is a bit of a stretch to to Dupuytren’s, but it’s a start, if you are a rat, and possibly if you are human. Simple options are often the best. Keep looking for a cure!

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