Larsen’s insightful study and review of the demographics and microscopic anatomy of Dupuytren’s disease is over 50 years old, but reads like a recent publication. The author describes and ponders the significance of topics which were well known at the time: perivascular inflammation adjacent to but not within the affected areas; iron pigment in the center of active nodules. Non operative treatment with enzyme injections, nutritional supplements, radiotherapy are all discussed. Fasciotomy, fasciectomy and dermofasciectomy with skin graft are described and compared as are problems of postoperative stiffness and recurrence. Koch, Bruner, Boyes and Meyerding all comment. Fascinating, clear and delightful. http://www.dupuytrenfoundation.org/DupPDFs/1958_Larsen.pdf
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