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One Dup, Two Dup, Red Dup, Blue Dup

So much is known about Dupuytren; much more needs to be known. Dupuytren probably isn’t one single diagnosis or one single disease. It’s the end result of overlapping causes. It’s a late effect of many possible causes, the same way similar looking scars can be the late effects of different injuries – cuts, burns, blunt trauma and […]

Mother’s Day Maps

May is here. Summer is coming! In many countries, Mother’s day is being celebrated this Sunday. It’s a meaningful milestone. Dupuytren Research Group is also marking milestones – on a variety of maps. International Dupuytren Data Bank Enrollment The IDDB is nearing the 3000 enrollee mark: as of today, we have 2996 enrollees. Here is […]

Speeding up Dupuytren research

A hand surgery colleague just sent me hand pictures of a patient he had treated with needle aponeurotomy seven years ago. His patient recently had a recurrence and had an excellent outcome with repeat needle aponeurotomy. A great result, more impressive because things don’t always go as well. It’s an example of the ups and downs […]

First Dupuytren Nodule

My first Dupuytren palm nodule. What will to happen to me? Most Dupuytren disease starts as a nodule. Some nodules go away without any treatment. Some nodules develop minor cords and then seem to stop. Some nodules are the first sign of severe Dupuytren disease. Which is it going to be? Without a biomarker, we can […]

Dupuytren Contracture Procedure Choices

If a hand progresses from early Dupuytren disease (nodules, dimples, cords with no limitation of motion) to Dupuytren contracture, treatment should be considered.  The best compromise between the ordeal of a procedure and the best long term outcome is to treat either when the finger is either awkwardly bent or if the bend of one joint […]

IDDB, biomarkers and big data to cure Dupuytren disease

The International Dupuytren Data Bank (IDDB) will focus on Dupuytren biomarkers Why are biomarkers important for Dupuytren disease? Dupuytren contracture is an effect, not a cause. Think of fever. Fever is an effect of infection, drug reaction, or something else. Just treating the effect – the fever – doesn’t cure the cause. ‌‌ You have to find […]