Dupuytren Literature: Antidepressants / Serotonin

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Serotonin signalling is involved with some aspects of heart valve fibrosis, liver fibrosis, mediastinal and retroperitoneal fibrosis. It is also affected by some antidepressants.

  • Dees C, Akhmetshina A, Zerr P, Reich N, Palumbo K, Horn A, et al. Platelet-derived serotonin links vascular disease and tissue fibrosis. J Exp Med 2011;208:961–72. (PDF)
  • Macaulay D, Ivanova J, Birnbaum H, Sorg R, Skodny P. Direct and indirect costs associated with Dupuytren’s contracture . J Med Econ 2012; 15 :71–664. (PDF)
  • Mann D a., Oakley F. Serotonin paracrine signaling in tissue fibrosis. Biochim Biophys Acta – Mol Basis Dis 2013;1832:905–10. (PDF)
  • Ruddell RG, Oakley F, Hussain Z, Yeung I, Bryan-Lluka LJ, Ramm G a, et al. A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis. Am J Pathol 2006;169:861–76. (PDF)
  • de Almeida Prado PS, Soares MF, Lima FO, Schor N, Teixeira VPC. Amitriptyline aggravates the fibrosis process in a rat model of infravesical obstruction. Int J Exp Pathol 2012;93:218–24. (PDF)

Dupuytren Literature

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