DUPUYTREN LITERATURE: MECHANOBIOLOGY AND MECHANOTRANSDUCTION

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Medline Title Search (Dupuytren + (Mechanobiology or Mechanosensitive or Mechanotransduction or Contraction))

Selected Publications

• Aarabi Shahram, Bhatt Kirit A, Shi Yubin, Paterno Josemaria, Chang Edward I, Loh Shang A, Holmes Jeffrey W, Longaker Michael T, Yee Herman, Gurtner Geoffrey C. (2007). “Mechanical Load Initiates Hypertrophic Scar Formation through Decreased Cellular Apoptosis.” FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology 21 (12): 3250–61. http://www.fasebj.org/cgi/doi/10.1096/fj.07-8218com. (PDF)
• Afoke A, Meagher PJ, Starley I, McGrouther DA, Bailey AJ, Brown RA. Biomechanical characterization of tissues in Dupuytren’s disease. J Hand Surg Br. 1998;23(3):291-6. (PDF)
• Akaishi Satoshi, Akimoto Masataka, Ogawa Rei, Hyakusoku Hiko. (2008). “The Relationship between Keloid Growth Pattern and Stretching Tension: Visual Analysis Using the Finite Element Method.” Annals of Plastic Surgery 60 (4): 445–51. (PDF)
• Arany PR, Flanders KC, Kobayashi T, Kuo CK, Stuelten C, Desai K V., Tuan R, Rennard SI, Roberts AB. (2006). “ Smad3 Deficiency Alters Key Structural Elements of the Extracellular Matrix and Mechanotransduction of Wound Closure .” Proc Natl Acad Sci U S A 103 (24): 925–9250. (PDF)
• Arora PD, Bibby KJ, McCulloch C a G. Slow oscillations of free intracellular calcium ion concentration in human fibroblasts responding to mechanical stretch. J Cell Physiol. 1994;161(2):187-200. doi:10.1002/jcp.1041610202 (PDF)
• Bisson M. (2003). “The Contractile Properties of Fibroblasts Derived from Dupuytren’s Nodules and Cords and the Effects of TGF Beta1 Stimulation. A Thesis Submitted to the University of London for the Degree of Doctor of Medicine (M.D.).” (PDF)
• Bisson Marcus A, Beckett Kate S, McGrouther D Angus, Grobbelaar Adriaan O, Mudera Vivek. (2009). “ Transforming Growth Factor-beta1 Stimulation Enhances Dupuytren’s Fibroblast Contraction in Response to Uniaxial Mechanical Load within a 3-Dimensional Collagen Gel .” J Hand Surg Am 34 (6). Elsevier Inc.: 110–1102. (PDF)
• Bisson Marcus A, Mudera Vivek, McGrouther D Angus, Grobbelaar Adriaan O. (2004). “The Contractile Properties and Responses to Tensional Loading of Dupuytren’s Disease–Derived Fibroblasts Are Altered: A Cause of the Contracture?” Plastic and Reconstructive Surgery 113 (2): 611-621-624. (PDF)
• Brandes G, Reale E, Messina A. Microfilament system in the microvascular endothelium of the palmar fascia affected by mechanical stress applied from outside. Virchows Arch. 1996;429(2-3):165-72. (PDF)
• Chen Christopher S, Tan John, Tien Joe. (2004). “Mechanotransduction at Cell-Matrix and Cell-Cell Contacts.” Annual Review of Biomedical Engineering 6: 275–302. (PDF)
• Chin MS, Lancerotto L, Helm DL, et al. Analysis of neuropeptides in stretched skin. Plast Reconstr Surg. 2009;124(1):102-113. doi:10.1097/PRS.0b013e3181a81542 (PDF)
• Chin Michael S, Ogawa Rei, et al. (2010). “In Vivo Acceleration of Skin Growth Using a Servo-Controlled Stretching Device.” Tissue Engineering. Part C, Methods 16 (3): 397–405. http://www.liebertonline.com/doi/abs/10.1089/ten.tec.2009.0185. (PDF)
• Derderian Christopher A, Bastidas Nicholas, Lerman Oren Z, Bhatt Kirit A, Lin Shin E, Voss Jeremy, Holmes Jeffrey W, Levine Jamie P, Gurtner Geoffrey C. (2005). “Mechanical Strain Alters Gene Expression in an in Vitro Model of Hypertrophic Scarring.” Annals of Plastic Surgery 55 (1): 69–75. (PDF)
• Eddy RJ, Petro JA, Tomasek JJ. (1988). “Evidence for the Nonmuscle Nature of The ‘myofibroblast’ of Granulation Tissue and Hypertropic Scar. An Immunofluorescence Study.” The American Journal of Pathology 130 (2): 252–60. (PDF)
• Hadeed JG, Bond JE, Selim MA, Bergeron A, Levin LS, Levinson H. (2011). “Calcium-Dependent Signaling in Dupuytren’s Disease.” Hand (N Y) 6 (2): 159–64. (PDF)
• Gupta R, Allen F, Tan V, Bozentka DJ, Bora FW, Osterman AL. The effect of shear stress on fibroblasts derived from Dupuytren’s tissue and normal palmar fascia. J Hand Surg Am. 1998;23(5):945-50. (PDF)
• Halliday NL, Rayan Ghazi M, Zardi Luciano, Tomasek James J. (1994). “Distribution of ED-A and ED-B Containing Fibronectin Isoforms in Dupuytren’s Disease.” The Journal of Hand Surgery 19 (3): 428–34. (PDF)
• Hinz B, Celetta G, Tomasek JJ, Gabbiani G, Chaponnier C. (2001). “Alpha-Smooth Muscle Actin Expression Upregulates Fibroblast Contractile Activity.” Molecular Biology of the Cell 12 (9): 2730–41. (PDF)
• Howard Jeffrey C, Varallo Vincenzo M, Ross Douglas C, Roth James H, Faber Kenneth J, Alman Benjamin, Gan Bing Siang. (2003). “Elevated Levels of Beta-Catenin and Fibronectin in Three-Dimensional Collagen Cultures of Dupuytren’s Disease Cells Are Regulated by Tension in Vitro.” BMC Musculoskeletal Disorders 4 (July): 16. (PDF)
• Huang Chenyu, Ogawa Rei. (2012). “Fibroproliferative Disorders and Their Mechanobiology.” Connective Tissue Research 53 (3): 187–96. (PDF)
• Huang Xiangwei, Yang Naiheng, Fiore Vincent F, Barker Thomas H, Sun Yi, Morris Stephan W, Ding Qiang, Thannickal Victor J, Zhou Yong. (2012). “Matrix Stiffness-Induced Myofibroblast Differentiation Is Mediated by Intrinsic Mechanotransduction.” American Journal of Respiratory Cell and Molecular Biology 47 (3): 340–48. (PDF)
• Isaacson Janalee, Brotto Marco. (2014). “Physiology of Mechanotransduction: How Do Muscle and Bone ‘Talk’ to One Another?” Clinical Reviews in Bone and Mineral Metabolism 12 (2): 77–85. (PDF)
• Kim S-G, Akaike T, Sasagaw T, Atomi Y, Kurosawa H. Gene expression of type I and type III collagen by mechanical stretch in anterior cruciate ligament cells. Cell Struct Funct. 2002;27(3):139-144. http://www.ncbi.nlm.nih.gov/pubmed/12207044. (PDF)
• Komatsu I, Bond J, Selim A, Tomasek JJ, Levin LS, Levinson H. (2010). “ Dupuytren’s Fibroblast Contractility by Sphingosine-1-Phosphate Is Mediated through Non-Muscle Myosin II .” J Hand Surg Am 35 (10): 158–1580. (PDF)
• Komatsu Issei, Levin L Scott, Selim Angelica, Levinson Howard. (2009). “Dupuytren’s Disease and Fibroblast Contractility.” The Journal of Hand Surgery 34 (7). American Society for Surgery of the Hand: 19–20. (PDF)
• Moore SW, Roca-Cusachs P, Sheetz MP. Stretchy proteins on stretchy substrates: The important elements of integrin-mediated rigidity sensing. Dev Cell. 2010;19(2):194-206. doi:10.1016/j.devcel.2010.07.018 (PDF)
• Moyer KE, Banducci DR, Graham 3rd WP, Ehrlich HP. (2002). “Dupuytren’s Disease: Physiologic Changes in Nodule and Cord Fibroblasts through Aging in Vitro.” Plastic and Reconstructive Surgery 110 (1): 187-93-6. (PDF)
• Munevar S, Wang Y-L, Dembo M. Regulation of mechanical interactions between fibroblasts and the substratum by stretch-activated Ca2+ entry. J Cell Sci. 2004;117(Pt 1):85-92. doi:10.1242/jcs.00795 (PDF)
• Nekouzadeh A, Pryse KM, Elson EL, Genin GM. Stretch-activated force shedding, force recovery, and cytoskeletal remodeling in contractile fibroblasts . J Biomech . 2008;41(14):271-2964. doi:10.1016/j.jbiomech.2008.07.033 (PDF)
• Ogawa R, Okai K, Tokumura F, et al. The relationship between skin stretching/contraction and pathologic scarring: The important role of mechanical forces in keloid generation. Wound Repair Regen. 2012;20(2):149-157. doi:10.1111/j.1524-475X.2012.00766.x (PDF)
• Orr a Wayne, Helmke Brian P, Blackman Brett R, Schwartz Martin a. (2006). “Mechanisms of Mechanotransduction.” Developmental Cell 10 (1): 11–20. (PDF)
• Parizi M, Howard EW, Tomasek JJ. (2000). “Regulation of LPA-Promoted Myofibroblast Contraction: Role of Rho, Myosin Light Chain Kinase, and Myosin Light Chain Phosphatase.” Experimental Cell Research 254 (2): 210–20. (PDF)
• Piersma Bram, Rond Saskia De, Werker Paul MN, Boo Stellar, Hinz Boris, Beuge Marike M Van, Bank Ruud A. (2015). “YAP1 Is a Driver of Myo Fi Broblast Differentiation in Normal and Diseased Fibroblasts.” The American Journal of Pathology, no. October: 1–13. (PDF)
• Rayan GM, Parizi M, Tomasek JJ. (1996). “Pharmacologic Regulation of Dupuytren’s Fibroblast Contraction in Vitro.” Journal of Hand Surgery 21 (6): 1065–70. (PDF)
• Rayan GM, Tomasek JJ. (1994). “Generation of Contractile Force by Cultured Dupuytren’s Disease and Normal Palmar Fibroblasts.” Tissue & Cell 26 (5): 747–56. (PDF)
• Raykha C, Crawford J, Gan BS, Fu P, Bach LA, O’Gorman DB. (2013). “IGF-II and IGFBP-6 Regulate Cellular Contractility and Proliferation in Dupuytren’s Disease.” Biochim Biophys Acta 1832 (10): 1511–19. (PDF)
• Ruwhof C, van Wamel a E, Egas JM, van der Laarse a. Cyclic stretch induces the release of growth promoting factors from cultured neonatal cardiomyocytes and cardiac fibroblasts. Mol Cell Biochem. 2000;208(1-2):89-98. http://www.ncbi.nlm.nih.gov/pubmed/10939632. Accessed October 9, 2013. (PDF)
• Sanders JL, Dodd C, Ghahary A, Scott PG, Tredget EE. (1999). “The Effect of Interferon-alpha2b on an in Vitro Model Dupuytren’s Contracture.” J Hand Surg Am 24 (3): 578–85. (PDF)
• Satish L, O’Gorman DB, Johnson S, Raykha C, Gan BS, Wang JH, Kathju S. (2013). “ Increased CCT-Eta Expression Is a Marker of Latent and Active Disease and a Modulator of Fibroblast Contractility in Dupuytren’s Contracture .” Cell Stress Chaperones 18 (4): 397–404. (PDF)
• Schleip R, Duerselen L, Vleeming A, et al. Strain hardening of fascia: static stretching of dense fibrous connective tissues can induce a temporary stiffness increase accompanied by enhanced matrix hydration. J Bodyw Mov Ther. 2012;16(1):94-100. doi:10.1016/j.jbmt.2011.09.003 (PDF)
• Schultz RJ, Tomasek JJ. (1990). “Cellular Structure and Interconnections.” In Dupuytren’s Disease Biology and Treatment, 86–98. (PDF)
• Skutek M, van Griensven M, Zeichen J, Brauer N, Bosch U, Zeichen GJ. Cyclic mechanical stretching modulates secretion pattern of growth factors in human tendon fibroblasts. Eur J Appl Physiol. 2001;86(1):48-52. doi:10.0007/s004210100502 (PDF)
• Staats Kim A, Wu Timothy, Gan Bing S, O’Gorman David B, Ophoff Roel A. (2016). “Dupuytren’s Disease Susceptibility Gene, EPDR1, Is Involved in Myofibroblast Contractility.” Journal of Dermatological Science 83 (2): 131–37. (PDF)
• Tarlton JF, Meagher P, Brown RA, McGrouther DA, Bailey AJ, Afoke A. (1998). “Mechanical Stress in Vitro Induces Increased Expression of MMPs 2 and 9 in Excised Dupuytren’s Disease Tissue.” Journal of Hand Surgery (Edinburgh, Scotland) 23 (3): 297–302. (PDF)
• Tarpila E, Ghassemifar M, Wingren S, Agren M, Franzen L. (1996). “ Contraction of Collagen Lattices by Cells from Dupuytren’s Nodules .” The Journal of Hand Surgery: Journal of the British Society for Surgery of the Hand 21 (6): 801–5. (PDF)
• Tomasek J, Rayan GM. (1995). “Correlation of Alpha-Smooth Muscle Actin Expression and Contraction in Dupuytren’s Disease Fibroblasts.” J Hand Surg Am 20 (3): 450–55. (PDF)
• Tomasek JJ, Gabbiani G, Hinz B, Chaponnier C, Brown RA. (2002). “ Myofibroblasts and Mechano-Regulation of Connective Tissue Remodelling .” Nat Rev Mol Cell Biol 3 (5): 63–349. (PDF)
• Tomasek JJ, Haaksma CJ, Eddy RJ, Vaughan MB. (1992). “Fibroblast Contraction Occurs on Release of Tension in Attached Collagen Lattices: Dependency on an Organized Actin Cytoskeleton and Serum.” The Anatomical Record 232 (3): 359–68. (PDF)
• Tomasek JJ, Schultz RJ, Episalla CW, Newman Stuart A. (1986). “The Cytoskeleton and Extracellular Matrix of the Dupuytren’s Disease ‘myofibroblast’: An Immunofluorescence Study of a Nonmuscle Cell Type.” The Journal of Hand Surgery 11 (3): 365–71. (PDF)
• Tomasek JJ, Schultz RJ, Haaksma CJ. (1987). “Extracellular Matrix-Cytoskeletal Connections at the Surface of the Specialized Contractile Fibroblast (Myofibroblast) in Dupuytren Disease.” The Journal of Bone and Joint Surgery. American Volume 69 (9): 1400–1407. (PDF)
• Tomasek JJ, Vaughan MB, Haaksma CJ. (1999). “Cellular Structure and Biology of Dupuytren’s Disease.” Hand Clin 15 (1): 21–34. (PDF)
• Tomasek James J, Vaughan Melville B, Kropp Bradley P, Gabbiani Giulio, Martin Michael D, Haaksma Carol J, Hinz Boris. (2006). “Contraction of Myofibroblasts in Granulation Tissue Is Dependent on Rho/Rho Kinase/myosin Light Chain Phosphatase Activity.” Wound Repair and Regeneration 14 (3): 313–20. (PDF)
• Townley WA, Cambrey AD, Khaw PT, Grobbelaar AO. (2009). “The Role of an MMP Inhibitor in the Regulation of Mechanical Tension by Dupuytren’s Disease Fibroblasts.” The Journal of Hand Surgery, European Volume 34 (6): 783–87. (PDF)
• Townley William A, Cambrey Alison D, Khaw Peng T, Grobbelaar Adriaan O. (2008). “Matrix Metalloproteinase Inhibition Reduces Contraction by Dupuytren Fibroblasts.” Journal of Hand Surgery 33 (9): 1608–16. (PDF)
• Tse R, Howard J, Wu Y, Gan BS. (2004). “ Enhanced Dupuytren’s Disease Fibroblast Populated Collagen Lattice Contraction Is Independent of Endogenous Active TGF-beta2 .” BMC Musculoskelet Disord 5 (1): 41. (PDF)
• Türker Tolga, Murphy Erin, Kaufman Christina L, Kutz Joseph E, Meister Edward a, Hoying James B. (2013). “Response of Dupuytren Fibroblasts to Different Oxygen Environments.” The Journal of Hand Surgery 38 (12). Elsevier Inc: 2365–69. (PDF)
• Van De Water Livingston, Varney Scott, Tomasek James J. (2013). “Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention.” Advances in Wound Care 2 (4): 122–41. (PDF)
• Vaughan MB, Howard EW, Tomasek JJ. (2000). “Transforming Growth Factor-beta1 Promotes the Morphological and Functional Differentiation of the Myofibroblast.” Experimental Cell Research 257 (1): 180–89. (PDF)
• Verhoekx Jennifer SN, Beckett Kate S, Bisson Marcus A, McGrouther Duncan A, Grobbelaar Adriaan O, Mudera Vivek. (2013). “The Mechanical Environment in Dupuytren’s Contracture Determines Cell Contractility and Associated MMP-Mediated Matrix Remodeling.” Journal of Orthopaedic Research 31 (2): 328–34. (PDF)
• Verhoekx Jennifer SN, Mudera Vivek, Walbeehm Erik T, Hovius Steven ER. (2013). “Adipose-Derived Stem Cells Inhibit the Contractile Myofibroblast in Dupuytren’s Disease.” Plastic and Reconstructive Surgery 132 (5): 1139–48. (PDF)
• Verhoekx Jennifer SN, Verjee Liaquat S, Izadi D David, Chan James KK, Nicolaidou V Vicky, Davidson Dominique D, Midwood Kim S, Nanchahal Jagdeep J. (2013). “Isometric Contraction of Dupuytren’s Myofibroblasts Is Inhibited by Blocking Intercellular Junctions.” J Invest Dermatol , May. Nature Publishing Group. (PDF)
• Verjee LS, Midwood K, Davidson D, Eastwood M, Nanchahal J. (2010). “Post-Transcriptional Regulation of Alpha-Smooth Muscle Actin Determines the Contractile Phenotype of Dupuytren’s Nodular Cells.” J Cell Physiol 224 (3): 681–90. (PDF)
• Vi Linda, Feng Lucy, Zhu Rebecca D, Wu Yan, Satish Latha, Gan Bing Siang, O’Gorman David B. (2009). “Periostin Differentially Induces Proliferation, Contraction and Apoptosis of Primary Dupuytren’s Disease and Adjacent Palmar Fascia Cells.” Experimental Cell Research 315 (20): 3574–86. (PDF)
• Viji Babu PK, Rianna C, Belge G, Mirastschijski U, Radmacher M. Mechanical and migratory properties of normal, scar, and Dupuytren’s fibroblasts. J Mol Recognit. 2018;31(9):e2719. (PDF)
• Wilkinson Janine M, Davidson Rose K, Swingler Tracey E, Jones Eleanor R, Corps Anthony N, Johnston Phillip, Riley Graham P, Chojnowski Adrian J, Clark Ian M. (2012). “MMP-14 and MMP-2 Are Key Metalloproteases in Dupuytren’s Disease Fibroblast-Mediated Contraction.” Biochimica et Biophysica Acta 1822 (6). Elsevier B.V.: 897–905. (PDF)
• Wong M, Mudera V. (2006). “Feedback Inhibition of High TGF-beta1 Concentrations on Myofibroblast Induction and Contraction by Dupuytren’s Fibroblasts.” Journal of Hand Surgery (Edinburgh, Scotland) 31 (5): 473–83. (PDF)
• Wu Miaozong, Fannin Jacqueline, Rice Kevin M, Wang Bin, Eric R. (2012). “Effect of Aging on Cellular Mechanotransduction” 10 (1): 1–15. (PDF)
• Yagmur Caglayan, Akaishi Satoshi, Ogawa Rei, Guneren Ethem. (2010). “Mechanical Receptor-Related Mechanisms in Scar Management: A Review and Hypothesis.” Plastic and Reconstructive Surgery 126 (2): 426–34. (PDF)
• Yang G, Crawford RC, Wang JH-C. Proliferation and collagen production of human patellar tendon fibroblasts in response to cyclic uniaxial stretching in serum-free conditions. J Biomech. 2004;37(10):1543-1550. doi:10.1016/j.jbiomech.2004.01.005 (PDF)
• Yano, H., et al. (2015). “Cellular mechanotransduction of physical force and organ response to exercise-induced mechanical stimuli.” The Journal of Physical Fitness and Sports Medicine 4(1): 83-91. (PDF)
• Zheng W, Seftor E a, Meininger CJ, Hendrix MJ, Tomanek RJ. Mechanisms of coronary angiogenesis in response to stretch: role of VEGF and TGF-beta. Am J Physiol Heart Circ Physiol. 2001;280(2):H909-H917. (PDF)