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Sex and Dupuytren’s in Boston

Dupuytren’s is fairly common in Boston, but seems different than the European flavor in terms of sex. The numbers on almost 2000 Boston Dupuytren’s patients were sorted out, and here’s how things roll in Boston: men develop Dupuytren’s almost twice as often as women, but it may seem like more because men tend to get the disease at a younger age, are almost twice as likely to have surgery if they do get Dupuytren’s, and are more likely to have recurrences after surgery. Why?