A recent study reported possible beneficial effects of caffeine on Dupuytren biology . There was 2011 study which reported similar results with forskolin, which affects the same cell chemistry as caffeine . Based on this, the possible use of caffeine was discussed in the Dupuytren Foundation blog in 2011 . Let’s look at two points in […]

Dupuytren disease advocacy faces many small challenges which collectively add up to a big challenge. Even the French word Dupuytren (“Doop-a-tren”) isn’t familiar to English speakers either in sound or spelling. It doesn’t even rhyme with any English word. The result is that the word Dupuytren is hard to remember, and often doesn’t register when people see […]

A hand surgery colleague just sent me hand pictures of a patient he had treated with needle aponeurotomy seven years ago. His patient recently had a recurrence and had an excellent outcome with repeat needle aponeurotomy. A great result, more impressive because things don’t always go as well. It’s an example of the ups and downs […]

My first Dupuytren palm nodule. What will to happen to me? Most Dupuytren disease starts as a nodule. Some nodules go away without any treatment. Some nodules develop minor cords and then seem to stop. Some nodules are the first sign of severe Dupuytren disease. Which is it going to be? Without a biomarker, we can […]

It has been a great year – thanks to you! We’ve launched the International Dupuytren Data Bank (IDDB) – research for a cure, to be the largest Dupuytren study in history. Now that the IDDB is underway, your support is more important than ever. Please consider increasing your year-end gift to the Dupuytren Foundation this year […]

Today is the day. The International Dupuytren Data Bank is now live. Independent. Crowdsourced. Massive. Free. The biggest Dupuytren research study ever. Enroll now at DupStudy.com Tell everyone with Dupuytren disease to enroll. DupStudy.com Together, we will find a cure.

It’s important to understand the difference between Dupuytren disease (any Dupuytren like changes in the hand – with or without contracture) and Dupuytren contracture (a bent finger due to Dupuytren like changes). An unsolved issue is variability of disease. It is not known what percent of people with early Dupuytren changes (a lump, a cord without contracture) will […]

Dupuytren disease has fallen through a gap in a system which ordinarily leads to better and better disease treatment. One side of the gap is that at its core, Dupuytren disease is a medical disorder, from some subtle biologic imbalance. The other side is that although Dupuytren disease does many things, Dupuytren hand deformity has […]

The May 2015 International Dupuytren Symposium in Groningen, The Netherlands was very productive. A textbook based on the proceedings is in the works. Video presentations are rolling out on http://Dupuytren.tv