Blog
Aggressive Dupuytren’s Disease
This report of Dupuytren’s extending from the palm into the forearm reviews the anatomy of involvement and points out the aggressive nature of Dupuytren’s in young people. We need more effective biologic treatments: https://dupuytrens.org/DupPDFs/1997_Sinha_1048.pdf
Dupuytren’ s Contracture – Microscopic Analysis
This is a classic article on the biology of Dupuytren’s. Structural changes in the palmar fascia are associated with type III collagen, which isn’t normally found in this tissue. Myofibroblasts are likely the source of this and are associated with disease recurrence.Most important quote: “Clinical recurrence was not related to
Dupuytren Symposium Website is Live!
The website for the 2010 International Symposium on Dupuytren’s Disease is now live, accepting on line registration and submission of abstracts for presentation. http://www.DupuytrenSymposium.com
Dupuytren Foundation is now a Public Charity
It’s taken almost two years to wade through the red tape, but hot off the press, The Dupuytren Foundation is finally officially certified as a 501(c)3 Public Charity! See 501(c)(3) certification for documentation.
First International Dupuytren’s Symposium
Plans are underway to organize the first International Symposium on Dupuytren’s Disease, to be held in South Florida May or June 2010, coordinated jointly by the Dupuytren Foundation and the Dupuytren Society. The goal of the symposium is to raise awareness regarding Dupuytren’s disease and related conditions and to promote
Dupuytren’s Skin Graft Controversy
Skin grafting is a time honored technique in the range of options to reduce the incidence of recurrence after fasciectomy for Dupuytren’s contracture. There are two general approaches. One is dermofasciectomy: remove a large area of affected skin and resurface the area with a similarly large skin graft. The other
Hand therapy and splinting are usually a big part of recovery after open surgery for Dupuytren’s contracture. Despite a drive for evidence based medicine, evidence for the effectiveness of splinting after open Dupuytren’s surgery is still elusive. Debbie Larson and Christina Jerosch-Herold review the issue in this article (link to
Dupuytren’s Foundation and Scripps Research
The Dupuytren’s Foundation http://www.dupuytrenfoundation.org has officially partnered with Scripps research to establish a DNA bank of tissues affected by Dupuytren’s disease. This will be available to researchers interested in studying Dupuytren DNA. So far, 20 samples have been collected. If the gene is identified, progress toward acure will be greatly
Needle Aponeurotomy
A new option is available for people who suffer from the bent fingers of Dupuytren’s contracture allowing patients to avoid the risks, ordeal and lengthy recovery associated with traditional open surgical techniques. This quick office procedure has been practiced in France for over 30 years, and is now catching on
Recent Dupuytren Publications
- Discussion: Frequency and Reporting of Complications after Dupuytren Contracture Interventions: A Systematic Review and Meta-Analysis
- The effect of preoperative interventions on postoperative outcomes following elective hand surgery: A systematic review
- Palmoplantar keratoderma, knuckle pads, and syndactyly associated with a new missense variant in the SLURP1 gene
- Post-traumatic Dupuytren's contracture in a paediatric patient: a case report and literature review
- Collagenase injection versus limited fasciectomy surgery to treat Dupuytren's contracture in adult patients in the UK: DISC, a non-inferiority RCT and economic evaluation
