DUPUYTREN LITERATURE: BETA-CATENIN / WNT

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βCatenin and WNT are involved in fibrosis and Dupuytren biology.

• Balaji KN, Kaveri S V, Bayry J. Wnt signaling and Dupuytren’s disease. N. Engl. J. Med. 2011 365(18):1740; author reply 1740. (PDF)
• Bowley E, O’Gorman DB, Gan BS. Beta-catenin signaling in fibroproliferative disease . J Surg Res 2007. 138 (1):50–141. (PDF)
• Degreef I, De Smet L, Sciot R, Cassiman J-J, Tejpar S. Immunohistochemical evidence for Zic1 coexpression with beta-catenin in the myofibroblast of Dupuytren disease. Scand. J. Plast. Reconstr. Surg. Hand Surg. 2009 43(1):36–40. (PDF)
• Degreef I, De Smet L, Sciot R, Cassiman J-JJ, Tejpar S. Beta-catenin overexpression in Dupuytren’s disease is unrelated to disease recurrence. Clin. Orthop. Relat. Res. 2009 467(3):838–45. (PDF)
• Dolmans GH, Werker PM, Hennies HC, Furniss D, Festen EA, Franke L, et al. Wnt signaling and Dupuytren’s disease. N. Engl. J. Med. 2011 365(4):307–17. (PDF)
• Howard JC, Varallo VM, Ross DC, Roth JH, Faber KJ, Alman B, et al. Elevated levels of beta-catenin and fibronectin in three-dimensional collagen cultures of Dupuytren’s disease cells are regulated by tension in vitro. BMC Musculoskelet. Disord. 2003 4:16. (PDF)
• Mosakhani N, Guled M, Lahti L, Borze I, Forsman M, Paakkonen V, et al. Unique microRNA profile in Dupuytren’s contracture supports deregulation of beta-catenin pathway. Mod Pathol 2010.23(11):152–1544. (PDF)
• O’Gorman DB, Wu Y, Seney S, Zhu RD, Gan BS. Wnt expression is not correlated with beta-catenin dysregulation in Dupuytren’s Disease. J. Negat. Results Biomed. 2006.5:13. (PDF)
• Raykha CN, Crawford JD, Burry AF, Drosdowech DS, Faber KJ, Gan BS, et al. IGF2 expression and ß-catenin levels are increased in Frozen Shoulder Syndrome. Clin. Invest. Med. 2014. (PDF)
• Shih B, Tassabehji M, Watson JS, Bayat A. DNA copy number variations at chromosome 7p14.1 and chromosome 14q11.2 are associated with dupuytren’s disease: potential role for MMP and Wnt signaling pathway . Plast Reconstr Surg 2012. 129 (4):32–921. (PDF)
• Degreef I, De Smet L, Sciot R, Cassiman JJ, Tejpar S. Beta-catenin overexpression in Dupuytren’s disease is unrelated to disease recurrence. Clin Orthop Relat Res. 2009 Mar;467(3):838-45. (PDF)
• ten Dam E-JPM, van Beuge MM, Bank RA, Werker PMN. Further evidence of the involvement of the Wnt signaling pathway in Dupuytren’s disease. J. Cell Commun. Signal. 2015. (PDF)
• van Beuge MM, ten Dam E-JPM, Werker PMN, Bank RA. Wnt pathway in Dupuytren’s disease, connecting pro-fibrotic signals. Transl. Res. 2015.166(6):762–71. (PDF)
• Varallo VM, Gan BS, Seney S, Ross DC, Roth JH, Richards RS, et al. Beta-catenin expression in Dupuytren’s disease: potential role for cell-matrix interactions in modulating beta-catenin levels in vivo and in vitro. 2003. 22 (2 ):364–3680. (PDF)
• Vi L, Gan BS, O’Gorman D. ADAM12 effects on Dupuytren’s Disease cell morphology and cytoplasmic beta catenin accumulation require Type I IGF receptor tyrosine kinase activity. McGill J. Med. 2007:175. (PDF)
• Vi L, Njarlangattil A, Wu Y, Gan BS, O’Gorman DB. Type-1 Collagen differentially alters beta-catenin accumulation in primary Dupuytren’s Disease cord and adjacent palmar fascia cells . BMC Musculoskelet Disord 2009. 10 :72. (PDF)