Video: I was a Teenage Myofibroblast (and I loved it!)
Before becoming the villain in Dupuytren’s, the myofibroblast was really not a bad cell. What happened? What caused the change? Could it happen to you? Professor Sem Phan, Department of Pathology, University of Michigan explains almost everything in this presentation of “Mechanisms of Myofibroblast Differentiation”: http://www.youtube.com/user/DupuytrenFoundation#p/u/0/dsPwSUDrz1Y Funding for these and other Dupuytren Symposium videos is […]
The Secret Life of Myofibroblasts: Dr. Boris Hinz reveals all!
Boris Hinz, PhD, University of Toronto, Ontario, CA, presents “Fundamental aspects of myofibroblast contraction.” and explains how the process is simple and complex. How do these little cells do such big things? More importantly, what steps in the process go wrong to result in Dupuytren’s, and what can be done to safely correct this? Watch […]
Dupuytren’s vs. Burns! Video: Dr. Paul Zidel at the 2010 Miami Dupuytren Symposium
Dr. Paul Zidel, Chief, Hand Surgery, Maricopa Medical Center, Phoenix, Arizona, presents a thought provoking comparison of two different yet similar conditions in “Dupuytren’s versus burn scar contracture”http://www.youtube.com/user/DupuytrenFoundation#p/u/0/uR5OcoIKfOIHypertrophic scars, Ledderhose disease, burn scars, keloid scars, desmoid tumors, pulmonary fibrosis, arteriosclerosis and other abnormal fibrosing conditions share some of the same complex biology as Dupuytren’s. Answers […]
Video: Professor Millesi at the Miami Dupuytren’s Symposium
Professor Hanno Millesi of the Millesi Center in Vienna, chairman of the 1983 Dupuytren’s Meeting in Vienna, presents “Changes of the visco-elastic properties of the palmar fascia as the pathogenetic basis of Dupuytren’s Disease”: http://www.youtube.com/user/DupuytrenFoundation#p/u/0/vRc9XFBOVTk. The more one investigates, the deeper the mystery of Dupuytren’s becomes. The legendary Dr. Millesi explores the chicken and egg […]
Dr. Paul Werker presents at the 2010 Dupuytren Symposium
Paul Werker MD Ph.D., Professor and Head of the Department of Plastic Surgery, Groningen University Medical Center Groningen, NL, presents Management of soft tissue contractures: a surgical perspective. See the video at http://www.youtube.com/user/DupuytrenFoundation#p/u/0/fHoOhGlsgDU. This and other video presentations from the 2010 International Symposium on Dupuytren’s Disease are made possible through funding from the Dupuytren Foundation. […]
Video Presentations of the 2010 Miami Dupuytren Symposium on YouTube
The Miami Dupuytren Symposium was very exciting. Presentations were recorded on video, and are finally making their way through post processing to be available on line. Free. For you – courtesy of the Dupuytren Foundation. These will be released weekly. Each presentation is at least 15 minutes, and most will take some time to digest, […]
Stony Brook Dupuytren Symposium
I had the opportunity to attend the Stony Brook Dupuytren Symposium April 17. This was a real treat, featuring a faculty of well known authorities on Dupuytren’s. The volcanic ash European flight difficulties prevented attendance of only one speaker. The symposium covered a range of topics and in addition provided an in depth tour of […]
Stretching, Myofibroblasts and Dupuytren’s
How, and why, does Dupuytren’s disease actually contract? What is the physical mechanism? What provokes it? There is a genetic risk, but genes don’t provide the entire script, otherwise Dupuytren’s contractures should be symmetric, the same problem developing at the same time in the same way in both hands, but that’s not what happens: usually, […]
Personal experiences with Xiaflex and Needle Aponeurotomy
Xiaflex is now available, and is generating reports by both traditional writers and self published social media authors. There are now two minimally invasive treatments for contractures due to Dupuytren’s disease – Xiaflex injection and needle aponeurotomy – with relative advantages and disadvantages of each. The following video was made by a Dupuytren’s patient, documenting […]
Red wine and yellow curry to prevent Dupuytren’s?
Could a yellow curry dinner and a glass of red wine be good for Dupuytren’s? Possibly. Dupuytren’s is a fibrotic condition, something it shares with other disorders. There is a great deal of ongoing research into the biology of fibrosis and its possible treatment. Two studies suggest that diet may have an helpful influence on […]
