Dupuytren Contracture Procedure Choices
If a hand progresses from early Dupuytren disease (nodules, dimples, cords with no limitation of motion) to Dupuytren contracture, treatment should be considered. The best compromise between the ordeal of a procedure and the best long term outcome is to treat either when the finger is either awkwardly bent or if the bend of one joint […]
Dupuytren Disease versus Dupuytren Contracture
What is the difference between Dupuytren Disease and Dupuytren Contracture? Dupuytren Disease is condition in which there is an imbalance in the body’s ability to regulate part of the biology involved in healing and scarring. The medical name for the changes caused by Dupuytren disease is fibrosis: tough, scar like tissue forms where it doesn’t belong. […]
IDDB, biomarkers and big data to cure Dupuytren disease
The International Dupuytren Data Bank (IDDB) will focus on Dupuytren biomarkers Why are biomarkers important for Dupuytren disease? Dupuytren contracture is an effect, not a cause. Think of fever. Fever is an effect of infection, drug reaction, or something else. Just treating the effect – the fever – doesn’t cure the cause. You have to find […]
GivingTuesday Deal for the Dupuytren Foundation
It has been a great year – thanks to you! We’ve launched the International Dupuytren Data Bank (IDDB) – research for a cure, to be the largest Dupuytren study in history. Now that the IDDB is underway, your support is more important than ever. Please consider increasing your year-end gift to the Dupuytren Foundation this year […]
Three types of Dupuytren disease?
It’s important to understand the difference between Dupuytren disease (any Dupuytren like changes in the hand – with or without contracture) and Dupuytren contracture (a bent finger due to Dupuytren like changes). An unsolved issue is variability of disease. It is not known what percent of people with early Dupuytren changes (a lump, a cord without contracture) will […]
Options For Severe Dupuytren Recontracture 2/2
The three traditional treatments for severe recurrent Dupuytren contracture are PIP joint fusion, dermofasciectomy and amputation. These have been reviewed here. The list of alternative approaches is growing, particularly for the most difficult problem of PIP joint recontracture. The problem is that over time, the tendons and ligaments of a bent PIP joint change and […]
Will Winford’s Dupuytren Challenge: Climbing El Capitán for a Cure
Dupuytren disease is a challenge. So is climbing straight up the side of a tall mountain with your bare hands. Today Will Winford, a 27 year old rock climber with Dupuytren disease, begins his conquest of both – climbing the 3000 vertical feet of El Capitán and using this to help raise awareness of Dupuytren disease. Find […]
The Knowledge Gap
Dupuytren disease has fallen through a gap in a system which ordinarily leads to better and better disease treatment. One side of the gap is that at its core, Dupuytren disease is a medical disorder, from some subtle biologic imbalance. The other side is that although Dupuytren disease does many things, Dupuytren hand deformity has […]
Blue Eyes, Dupuytren Disease, and Alcoholism
A recent study linked blue eyes with genetic risk for alcoholism. Interesting, because Dupuytren disease is more common in people with light colored eyes and according to some studies, Dupuytren is linked to chronic alcoholism. It’s a match! Or is it? Other studies conclude alcoholism is not a risk for Dupuytren disease. Both Dupuytren and blue eyes are more common in […]
Big data editorial
The path to understanding Dupuytren disease is built on evolving technologies: patient crowdsourcing, genetic analysis, and big data. We’re not alone. (Post updated 12/4/2023: It discussed http://www.amjorthopedics.com/uploads/media/ajo043090399.pdf, which is no longer available. Big data is now not quite as big…).
