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Scientific breakthroughs at the Miami Dupuytren Symposium

It’s been a few months since the 2010 International Symposium on Dupuytren’s Disease in Miami, FL. This was a huge undertaking – the first meeting of this scope and magnitude in 20 years, showcasing some incredible new developments. There was so much material presented that it’s taking a while to

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Miami International Dupuytren Symposium Breaks New Ground

Medical researchers and physicians from 15 countries converge May 22 and 23 at the Intercontinental Hotel in Miami for an intensive two day summit on Dupuytren’s Disease: www.DupuytrenSymposium.com. Dupuytren’s disease is a progressive condition which gradually curls the fingers permanently into the palm. It is estimated that 3 to 9

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Stony Brook Dupuytren Symposium

I had the opportunity to attend the Stony Brook Dupuytren Symposium April 17. This was a real treat, featuring a faculty of well known authorities on Dupuytren’s. The volcanic ash European flight difficulties prevented attendance of only one speaker. The symposium covered a range of topics and in addition provided

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Stretching, Myofibroblasts and Dupuytren’s

How, and why, does Dupuytren’s disease actually contract? What is the physical mechanism? What provokes it? There is a genetic risk, but genes don’t provide the entire script, otherwise Dupuytren’s contractures should be symmetric, the same problem developing at the same time in the same way in both hands, but

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Personal experiences with Xiaflex and Needle Aponeurotomy

Xiaflex is now available, and is generating reports by both traditional writers and self published social media authors. There are now two minimally invasive treatments for contractures due to Dupuytren’s disease – Xiaflex injection and needle aponeurotomy – with relative advantages and disadvantages of each. The following video was made

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Red wine and yellow curry to prevent Dupuytren’s?

Could a yellow curry dinner and a glass of red wine be good for Dupuytren’s? Possibly. Dupuytren’s is a fibrotic condition, something it shares with other disorders. There is a great deal of ongoing research into the biology of fibrosis and its possible treatment. Two studies suggest that diet may

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A personal look at Dupuytren’s

A family physician remembers his late father’s Dupuytren’s and muses on options for treatment: http://www.greatfallstribune.com/article/20100309/LIFESTYLE/3090307/Hands+become+claws+in+victims+of+Dupuytren+s. The observation “…in his final years he was wearied by the thought of ‘another procedure’ or treatment and decided to live with the condition” is a telling testimony for the need for better treatment options

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Dupuytren’s or palmar fasciitis?

Dupuytren’s isn’t the only problem which can affect the fascia of the palm. Inflammation of the palmar fascia (palmar fasciitis) may be due to less common problems, and differs from typical Dupuytren’s in that it is usually painful. The difference between Dupuytren’s and palmar fasciitis is similar to the difference

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Metalloproteinases and Dupuytren’s

A better understanding of the biology of metalloproteinases may lead to new treatment options for Dupuytren’s. Metalloproteinases (MMPS) are a group of enzymes in our bodies which break down certain proteins, including collagen. MMPS are blocked by tissue inhibitors of metalloproteinases (TIMPS). MMPS and TIMPS balance each other: imbalances have

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