Biomarkers

Dupuytren Triggers: 60 second survey
Dec 16, 2017

Dupuytren Triggers Yes, that’s a picture of Roy Roger’s horse, Trigger. You might not have been expecting that. Dupuytren also shows up unexpectedly. People have normal hands, and then they don’t. Many feel the problem came out of nowhere. Others may recall some event happening around the same time as Dupuytren first appeared and conclude […]

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How common is Dupuytren Disease?
On: Apr 1, 2017
By: Charles Eaton

How common is Dupuytren disease? The short answer is this:  much more common than you might think. Scroll to the bottom to get the summary numbers. For the long answer, keep reading. The details depend on where you get your data. One set of data comes from a large web-based survey (DiBenedetti 2010). One conclusion […]

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Cannabinoids, Dupuytren, and Orphan Drugs
On: Mar 3, 2017
By: Charles Eaton

I was recently asked if medical marijuana might be helpful for Dupuytren disease. The short answer is “No one knows.”. The longer answer is much more interesting. The late effect of Dupuytren disease is Dupuytren contracture. The medical term for the findings in Dupuytren contracture is fibrosis. Sclerosis also means the same thing. If either of […]

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Happy Valentine’s Day from Dupuytren Research Group!
On: Feb 14, 2017
By: Charles Eaton

Two Dupuytren stories for this Valentine’s Day. First, Saint Valentine. There were nearly a dozen people called Saint Valentine. Did this one have Dupuytren Contracture? He’s clearly in the high risk demographic – an old Caucasian man. Looks like he’s got it, but we’ll never know. It is important to know that there’s a lot […]

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The Future is Coming!

Improving the Future of Dupuytren Care Right now, many people with mild Dupuytren biology do well after surgery or after Xiaflex – because most people have mild to moderate Dupuytren biology. The issue isn’t the patient with mild disease biology who will do well for a long time after any treatment. The issue is those […]

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Happy Thanksgiving from the Dupuytren Foundation!

Turkey Day Update! Much has happened since the last Dupuytren Foundation report in July. The International Dupuytren Data Bank (IDDB) averages 100 new enrollees each month. We’re continuing to work out the complicated details of blood testing. If you haven’t enrolled yet, now is the time: http://DupStudy.com. Our international research committee continues to grow. So does […]

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Speeding up Dupuytren research

A hand surgery colleague just sent me hand pictures of a patient he had treated with needle aponeurotomy seven years ago. His patient recently had a recurrence and had an excellent outcome with repeat needle aponeurotomy. A great result, more impressive because things don’t always go as well. It’s an example of the ups and downs […]

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Biomarkers in Dupuytren Disease
IDDB, biomarkers and big data to cure Dupuytren disease
On: Dec 9, 2015
By: Charles Eaton

The International Dupuytren Data Bank (IDDB) will focus on Dupuytren biomarkers Why are biomarkers important for Dupuytren disease? Dupuytren contracture is an effect, not a cause. Think of fever. Fever is an effect of infection, drug reaction, or something else. Just treating the effect – the fever – doesn’t cure the cause. ‌‌ You have to find […]

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